Samuel Lee earned his bachelor's and master's degrees in electrical engineering from Texas A&M University and worked as an engineer at Texas Instruments. Called by God in 2014, he entered Dallas Theological Seminary (DTS), where he earned his Th.M. in 2018 and his Ph.D. in systematic theology in 2023. He is now Assistant Professor of Systematic Theology at DTS, teaching theology courses in both the English and Chinese programs.

He grew up at DCFC and was baptized in 2005. Samuel currently serves as DCFC's missions deacon. He serves in the English ministry, participating in preaching, Sunday school, and youth ministry, and is also an English teaching staff member and theological advisor for the Christian Bible Study Fellowship (CCF). His wife Febrina also earned her Th.M. from DTS and teaches Sunday school in the English ministry, leads short-term mission teams, and serves in children's ministry. They have two sons, Da'en (5) and Dazhi (4).